Biotech luxury skincare

1% PDRN · Sodium DNA · ADN sodique

NUCLEORA PDRN Radiance Serum — 30 mL airless pump bottle with a translucent DNA helix

Lightweight hydration.
Visible radiance, for sensitive skin.

Join the founding list

30 mL · Fragrance‑free · Airless pump

Join the founding list

24-hour early access before the public, and a 15% founding-member rate at launch week. A few considered emails, never noise.

Hydrates the skin.

Visibly plumper-looking skin.

Boosts skin's radiance.

The serum

NUCLEORA PDRN Radiance Serum

Sérum Éclat à l'ADN (PDRN 1 %)

  • 30 mL · airless pump. The formula stays sealed from air and fingers to the last dose.
  • 1% PDRN · Sodium DNA. Full raw-material input, not a label-deck trace.
  • Fragrance-free. Held as a written declaration, covering masking fragrances and essential oils.
  • Formulated for sensitive skin. Lightweight, water-based, quickly absorbed.

Nothing is for sale yet. The founding list shops first.

PDRN, explained without the hype

The active

PDRN, INCI name Sodium DNA, is a salmon-derived polynucleotide. It earned its reputation in Korean dermal aesthetics; we formulated it as a cosmetic, where it belongs in a daily routine.

The number on the label

Some serums carry an ingredient at a fraction of a percent: enough for the ingredient list, not for the formula. NUCLEORA uses a full 1% Sodium DNA raw-material input, and we publish the math: the raw material is supplied at 84–95% active, so the effective polynucleotide content in the finished formula is approximately 0.84–0.95%. You shouldn't have to email a brand to learn that.

What it's in there to do

In cosmetic terms: hydrate, support visibly plumper-looking skin, and boost radiance, working alongside a multi-humectant base of glycerin, sodium hyaluronate, beta-glucan and panthenol, with Ceramide EOP supporting the look of a healthy skin barrier.

What we won't say

A cosmetic hydrates and improves the appearance of skin. Promises beyond that belong to drugs, and you won't find them here: not on this page, not on the carton, not in an ad.

The ritual

Two drops, morning and evening

Pumped onto the fingertips and pressed over clean skin. Lightweight and fast-absorbing, fragrance-free for sensitive skin.

Why join now

  1. First access. The store opens to this list 24 hours before the public.
  2. The founding offer. A 15% founding-member rate at launch week, for this list only, applied automatically.
  3. A small first run. Our first production run is deliberately small and ships from British Columbia. When it's gone, the next batch takes as long as careful production takes.

No spam, no daily countdowns. A few considered emails between now and launch day.

Join the founding list

Built slowly, on purpose

NUCLEORA started with a simple observation: the active that reshaped Korean dermal aesthetics was everywhere in skincare conversation, and almost nowhere with honest numbers attached.

So we built one serum, properly. A full 1% Sodium DNA raw-material input. A fragrance-free formula for sensitive skin, in an airless pump that protects it. A bilingual label, because this brand is Canadian and the label should read like it. And a claims policy you can hold us to: if we can't support a sentence, we don't print it.

One product. No line extensions until this one has earned its place on your shelf.

NUCLEORA serum bottle and carton on a white bathroom shelf in soft morning light

The formula, openly

28 ingredients. The full INCI list is published before launch day, and the concentrations that matter are disclosed, not implied.

  • Sodium DNA1% raw-material input
  • GlycerinUSP pharmacopoeial grade
  • Niacinamidesupporting role
  • 3-O-Ethyl Ascorbic Acidvitamin C derivative
  • Sodium Hyaluronatehydration
  • Beta-Glucanhydration
  • Panthenolpro-vitamin B5
  • Ceramide EOPbarrier appearance

Salmon-derived Sodium DNA, disclosed plainly. This serum is not vegan, and we won't pretend otherwise.

The carton is the first impression

Macro of the NUCLEORA carton front panel showing the translucent DNA helix and matte soft-touch finish

Pale aqua, a translucent DNA helix, proof-blue type. The carton was designed and revised four times before we approved it, in both of Canada's official languages. Inside, a 30 mL airless pump: no jar oxidizing on a shelf, no dropper pulling air into the formula.

The unglamorous part, shown openly

Health Canada notification
Our Cosmetic Notification Form is filed with Health Canada before the first bottle ships.
Certified manufacturing
Produced with an ISO 22716-certified manufacturing partner.
Lot-by-lot inspection
Every production lot is sampled against a defined AQL standard. A single critical defect fails the lot.
Fragrance-free, in writing
Held as a signed declaration covering masking fragrances, perfume oils, and essential oils.
Bilingual by design
English and French with equal care, on every surface.
Questions or concerns
safety@nucleoraskin.com

Statements describe our regulatory process and documentation; they are not endorsements by any authority.

Questions, answered directly

What is PDRN?

PDRN stands for polydeoxyribonucleotide; on an ingredient list it appears as Sodium DNA. It's a salmon-derived polynucleotide best known from Korean dermal aesthetics. In this serum it's a cosmetic ingredient in a hydrating, radiance-focused formula.

Is the serum vegan?

No. Sodium DNA is salmon-derived, and we disclose that plainly.

I have sensitive skin. Is this for me?

The formula is fragrance-free and formulated for sensitive skin. As with any new product, patch test first; discontinue if irritation occurs. Consumers with severe seafood allergies should consult their physician before use.

What does "1%" actually mean?

It refers to the raw-material input: a full 1% of a Sodium DNA raw material that is 84–95% active, which works out to approximately 0.84–0.95% effective polynucleotide in the finished formula. We publish this because the number on a label should mean something.

When do you launch?

Summer 2026, Canada first. The founding list gets a 24-hour head start and the launch-week founding offer.

How much will it cost?

Full pricing is announced to the founding list first, in the early-access email. Shipping is free across Canada; only taxes are added at checkout.

Where do you ship?

Canada only at launch.

What happens with my email?

You'll receive a confirmation email (tap to confirm; that's how we keep the list clean), then a handful of considered emails before launch. Unsubscribe anytime, one click. Details in our Privacy Policy.

The first bottles
will have first owners.

Join the founding list: 24-hour early access, and the founding offer at launch week.